Warning: Do Not Order Protonitazene Online Without A Prescription Introduction The dangers of taking Protonitazene are real. This drug is a powerful central nervous system depressant. It is also habit-forming and can lead to addiction. Protonitazene is a Schedule II Controlled Substance in the United States. This means it has a high potential for abuse and dependence. The drug is only available by prescription and is not meant for recreational use. Those who take Protonitazene without a prescription are putting themselves at risk for overdose and death. The drug is dangerous and should only be taken under the care of a medical professional.